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Sherry F Queener Selected Research

piritrexim

5/2004Synthesis of 2,4-diamino-6-[2'-O-(omega-carboxyalkyl)oxydibenz[b,f]azepin-5-yl]methylpteridines as potent and selective inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase.
4/2003Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS.

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Sherry F Queener Research Topics

Disease

6Acquired Immunodeficiency Syndrome (AIDS)
03/2009 - 01/2003
4Infections
04/2013 - 11/2003
3Opportunistic Infections (Opportunistic Infection)
01/2018 - 06/2013
3Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
10/2011 - 09/2002
1Parasitic Diseases (Parasitic Disease)
10/2013
1Toxoplasmosis
02/2010
1Pneumonia (Pneumonitis)
03/2009
1Malaria
03/2008
1Neoplasms (Cancer)
07/2007
1HIV Infections (HIV Infection)
04/2003

Drug/Important Bio-Agent (IBA)

9Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA
10/2011 - 01/2003
4PyrimidinesIBA
01/2018 - 11/2003
3Biological ProductsIBA
01/2018 - 11/2003
3Folic Acid AntagonistsIBA
01/2018 - 04/2003
3Pharmaceutical PreparationsIBA
10/2013 - 09/2002
3Trimethoprim (Proloprim)FDA LinkGeneric
10/2011 - 04/2003
3Thymidine Monophosphate (TMP)IBA
10/2011 - 04/2003
2EnzymesIBA
03/2009 - 04/2003
2piritreximIBA
05/2004 - 04/2003
1Amino AcidsFDA Link
01/2018
1Thymidylate SynthaseIBA
10/2013
1Antiparasitic Agents (Antiparasitics)IBA
04/2013
1pyrimidineIBA
08/2008
1BiguanidesIBA
03/2008
14,6- diamino- 1,2- dihydro- 2,2- dimethyl- 1- (3- (2- chloro- 4- trifluoromethoxyphenoxy)propyloxy)- 1,3,5- triazineIBA
03/2008
1BoronIBA
07/2007
1nido-carboraneIBA
07/2007
1Proteins (Proteins, Gene)FDA Link
04/2005
1AzepinesIBA
05/2004
1EstersIBA
05/2004
1Antineoplastic Agents (Antineoplastics)IBA
11/2003
1Oxidoreductases (Dehydrogenase)IBA
04/2003
1dihydrofolateIBA
04/2003
1Pyrimethamine (Daraprim)FDA Link
09/2002

Therapy/Procedure

3Drug Therapy (Chemotherapy)
03/2004 - 09/2002
1Therapeutics
10/2011
1Boron Neutron Capture Therapy
07/2007